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Reducing the content of LCACs is an effective strategy to improve insulin sensitivity [73], and low acylcarnitine accumulation is conducive to improving insulin signaling and enhancing glucose uptake [74]

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The most commonly reported side effects are gastrointestinal issues, including nausea, vomiting, diarrhea, and stomach upset

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Ki67), a first-line molecular study (identification of hot spot mutations of BRAF and NRAS ) and an advanced molecular study (sequencing of NF1, KIT, BRAF, MAP2K1, GNAQ, GNA11, PLCB4, CYSLTR2, HRAS

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