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Many patients achieved clinically meaningful weight loss, and Saxenda became part of obesity management guidelines for those with BMI 30 (or 27 with comorbidity)
Pancreatitis Drug action on GLP-1 receptors of the pancreas and exocrine ducts may cause cellular overgrowth, hyperplasia, and duct occlusion
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In an oxidative ER environment, activated ERO1 generates disulfide bonds by consuming O 2 in the presence of flavin cofactors, which are then passed to the protein for folding via PDI (Wang et al., 2014)
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