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A meta-analysis covering over 28,000 patients found that while the overall rate of GI adverse events was similar (approximately 5253% of patients in both groups), serious adverse events occurred somewhat more frequently with higher tirzepatide doses (5.37% at 1015 mg) compared to semaglutide (2.8%)
The choice depends on the research setup, not the peptide itself
Could personalized exercise prescriptions and targeted nutritional interventions mitigate these potential adverse effects while optimizing metabolic outcomes
You know, several years ago, about a decade now, they did a trial to look at the impact of these medications on cardio vascular risk, predominantly because there was a concern that they may increase the risk for heart disease, not necessarily a decrease, but in fact, they found that beyond the fact that its safe for patients with cardiovascular disease, it actually reduced the risk of getting cardiovascular events like heart attacks and strokes
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