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In individuals homozygous for the C677T polymorphism in the MTHFR gene, low riboflavin status is associated with elevated plasma homocysteine, and in turn linked with a higher risk of cardiovascular disease and other chronic diseases (13, 14)

Further analysis revealed that plasma L-Cn levels were positively correlated with serum levels of total bilirubin, direct bilirubin, and indirect bilirubin, but not with the serum albumin levels, creatinine concentration, and liver stiffness ( Figure 1D )

Transplantation may help selected patients after stabilization

Metabolic improvements in blood pressure, triglycerides, and blood sugar become measurable