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Despite the observed increase in heart rate, several meta-analyses have demonstrated that GLP-1RAs are associated with a lower risk of AF compared with other glucose-lowering agents, suggesting their potential protective effect against AF occurrence (131, 148)
Consistent with these findings, our present and previous studies confirmed that endothelium-dependent vasodilation is significantly impaired in IGF- 1R KD mice [22, 44]
Mitochondrial outer membrane permeabilization increases reactive oxygen species production and decreases mean sperm velocity but is not associated with DNA fragmentation in human sperm
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