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Some early research and clinical discussion suggest GLP-1 pathways may influence mast cell activity, inflammatory signaling, and immune regulation, which is why they are gaining interest in MCAS and histamine intolerance care

These include slowing gastric emptying, supporting insulin secretion, modulating appetite, and influencing how nutrients are digested and absorbed

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Important Precautions for Oral Medications The interaction between Zepbound and omeprazole highlights a broader rule for anyone on GLP-1 or GIP medications: oral medications may behave differently