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In general, theres either no change in depression score or theres a slight improvement. While the results are encouraging, more research is needed to study the psychiatric effects of semaglutide on patients with obesity who have clinically significant depression or other mental health conditions, Kushner said

MTHFR = 5,10-methylene-THF reductase

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This means that patients had fewer other illnesses linked to diabetes and lower health costs as a result