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LOXL4 is induced by transforming growth factor 1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling

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This inhibitory action, which is in accord with opposing effects of various metalloporphyrins on HMOX,15 might contribute to anti-carcinogenic effects observed in our study and also, at least in part, account for chemopreventive effects of chlorophyll-rich nutrients

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