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doi: 10.1016/j.arcmed.2021.03.006 126 WyattJFernandoSMPowellSGHillCJArshadIProbertCet al

Large-scale human trials evaluating lifespan, disease prevention, or long-term aging outcomes do not currently exist

It is a commonly accepted fact that wounds in diabetic patients exhibit decreased levels of angiogenic factors, resulting in impairment of angiogenesis [128, 129]