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In vivo and in vitro models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expression of genes related to glutathione anabolic metabolism (GCLC, GCLM, and SLC7A11) was significantly down-regulated
"With good counseling, steady weight loss, and attention to nutrition, most patients can continue therapy safely." GLP-1s are a class of drugs that mimic natural hormones
Strength training plays a major role, and patients often ask can you gain muscle on GLP-1 while working to preserve metabolism
Presented for research literature review only Miotto G et al
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