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& Hammond, C
After 72 weeks: Participants taking 5 mg of tirzepatide lost 15% of their starting body weight on average Those taking 10 mg lost an average of 19.5% Those taking the highest dose, 15 mg, lost an average of 20.9% Another phase 3 clinical trial studied the efficacy of once-daily orforglipron in people with obesity and found that it resulted in significant weight loss compared to placebo
Moreover, researchers are exploring whether different GLP-1 agonists (such as semaglutide and liraglutide ) vary in effectiveness for different types of addiction, and whether individual factors such as age, gender, or genetic makeup influence how well these treatments work
Little information is available on stability, but one study found it to be stable in water between pH 4.5-7.4 at 60C for at least two weeks, suggesting both aqueous and some thermal stability
