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2025;17(12):e98858
For subjects treated with the highest dose of tirzepatide (15 mg per week), the risk to develop any major adverse cardiovascular event (MACE-4 composed of myocardial infarction, stroke, hospitalization for angina, and all-cause death) was estimated at 050 (026095)
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This is in terms of enhanced insulin secretion by stimulating both GIPR and GLP-1R on -cells
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