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Apparently, GLP-1RAs can be the basis of promising methods of transdiagnostic mechanistically based therapy and prevention in various fields of neuropsychiatric pathology, including general cognitive systems, reward and motivation systems

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D2R-GHSR1a dimer When Kern et al

Chronic administration of amylin and GLP-1R analogs does not affect amylin- and GLP-1-related gene expression in the DVC of adult rats To determine whether the profound degree of sustained weight loss observed with chronic administration of amylin and GLP-1R analogs could potentially affect the expression of amylin- and/or GLP-1- ligand/receptor expressing cells in the DVC, we performed qPCR analyses on micro-punched DVC tissue collected from our animals at the termination of the chronic experiment