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IM injections go deeper into the muscle, allowing the medication to be absorbed more quickly into the bloodstream
The positive outcomes are currently based on a large body of clinical experience and anonymized case reports rather than large trial data
Those taking tirzepatide, managed an additional 5.5% WL from randomisation, compared to those taking placebo who experienced mean weight regain of 14% from randomisation [49]
An important point is the direction of flow through gaps that are not sealed can be either into or out of the intestinal wall
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