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GHK-Cu was first identified by Loren Pickart in 1973 while studying a fraction of human plasma albumin that caused old liver tissue to synthesize proteins characteristic of younger tissue
This impairs Notch2 degradation and sustains oncogenic Notch2 signaling, which upregulates c-Myc and Cyclin D3 expression
It aids in the elimination of toxins, heavy metals, and pollutants from the body, which can have a direct impact on skin health
But the peptide therapies being touted online for their wellness and longevity benefits have not undergone large-scale, rigorous clinical trials involving humans
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