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Initially approved in 2005 with Exenatide (Byetta), these drugs were designed to improve glycemic control in type 2 diabetes
Since the availability of the antioxidant system determines ROS concentration, this system contributes to conflicting biological activities, such as cell fate, i.e., survival or death
Perhaps the most direct chronobiotic from diet is melatonin itself
In regenerative medicine, stem cells are also meant to be used to replace gland cells that have been destroyed by processes (Klubo-Gwiezdzinska And Wartofsky 2022)
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