Metformin inhibits adenosine 5monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons
doi: 10.3389/fphar.2024.1461398 Received 08 July 2024 Accepted 01 November 2024 Published 13 November 2024 Volume 15 - 2024 Edited by Daniele Maria-Ferreira, Instituto de Pesquisa Pel Pequeno Prncipe, Brazil Reviewed by Kimberly Crosby, University of Oklahoma, United States Marcelo Adrian Estrin, Interamerican Open University, Argentina Qiuxia Min, The First Peoples Hospital of Yunnan Province, China Updates Copyright 2024 Guo, Guo, Li and Wang
They support immune health, reduce inflammation, enhance mental clarity, and protect cells from oxidative stress promoting total body rejuvenation and long-term wellness
Common side effects are typically gastrointestinal, such as nausea or constipation, and are usually managed by starting with a low dose and titrating up slowly under medical guidance