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Zhao J, Dar HH, Deng Y, St Croix CM, Li Z, Minami Y

What they found: Erectile response in 80 % of subjects in the Melanotan II group vs 20 % placebo Mean time to erection: 45 minutes Mean duration of erection: 90 minutes Subjectively satisfactory penetrative capability in 70 % Nausea in 50 % of subjects Why it matters: This was the first clinical demonstration of the melanocortin mechanism for erectile function

Blockade of cellular energy metabolism through 6-aminonicotinamide reduces proliferation of non-small lung cancer cells by inducing endoplasmic reticulum stress

During hyperglycemia, GIP potentiates glucose-induced insulin secretion without exhibiting a glucagonotropic effect (35)