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Other Safety Considerations A comprehensive review of post-marketing safety data identified that both drugs have been associated with gastrointestinal issues (nausea, vomiting, pancreatitis, diarrhea) as well as potential effects on bone remodeling, kidney function, and thyroid health
In the SURMOUNT-1 trial, participants without diabetes lost an average of 15-20% of their body weight over 72 weeks, depending on the dose (5 mg, 10 mg, or 15 mg weekly)
By recognizing these rare complications early, providers can ensure safer outcomes and maintain long-term health
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