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Dose conversion between animals and human
This precise delivery guarantees that the nanoparticles arrive at the designated cells, minimizing toxicity and off-target effects (92)
Similarly, Jia et al (91) reported that elevated neuronal lactate uptake augments ROS production and mitochondrial oxidative metabolism, thereby disrupting the balance between ROS generation and detoxification, impairing ATP synthesis and ultimately leading to peripheral axonal degeneration
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