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In the simplest version, transwell models represent endothelial cells cultured on a matrix-coated permeable membrane inserts for the standard cell culture plates, which divide the cultivation well into two parts, imitating the blood-facing and brain-facing compartments of the barrier
Together, they are investigated for complementary activity across multiple endocrine and systemic pathways in experimental settings
Donescu D, Nistor CL, Purcar C, Petcu C, Serban S, Corobea MC, Ghiurea M: Formation and dissolution of silver nanoparticles
Keatings VM, Barnes PJ
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