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By mimicking the pulse that your body is already built around, rather than forcing it to rely on artificial means of release, you are working within your biology, not against it

The levels of CD144 (VE-cadherin) or CD31-positive exosomes in circulation directly reflect the physical dissociation of endothelial intercellular junction complexes (105), while the accompanying high expression of Ang-2 further confirms the loss of shear stress sensing mechanisms and severe microvascular injury (106)