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A phase 3 trial (the final set of trials before a drug manufacturer seeks FDA approval) in adults with obesity or overweight and at least one obesity-related complication found that CagriSema helped participants lose an average 20.4% of their body weight at 68 weeks of treatment, compared with 3% in the placebo group

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In the REDEFINE 1 phase 3 trial, cagrilintide 2.4 mg monotherapy produced an average body weight reduction of 11.8% over 68 weeks