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Also, two nutrients (vitamin E and selenium) did not even reach their RDI
Understanding this mechanism helps contextualise why menstrual changes may occur during significant weight loss, whether achieved through medication, diet, or lifestyle modification
Chatzinikita E, Maridaki M, Palikaras K, Koutsilieris M, Philippou A
These include: Nausea (reported in a significant proportion of participants, particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and tended to diminish over time
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