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Because it is an injection, it should always be given by a trained provider, and we start every patient with a consultation and testing to confirm the treatment is right for them

When your levels are low, it can affect your entire sense of well-being, leading to issues like anemia or neurological problems

Step 4: Prepare the injection If your medication comes in an ampoule, carefully snap it open (you can use your fingers or an ampoule breaker)

Inject subcutaneously at a clean, rotated site abdomen, thigh, or upper arm For how to manage any side effects during titration, see our [semaglutide side effects guide](/guides/semaglutide-side-effects-how-to-manage)