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Subsequent research, including a 2021 study published in Neural Plasticity, further clarified the mechanism, showing that this pathway works partly through beta-endorphin release mediated by IL-10 [16]

The other authors report no conflicts of interest relevant to this article

Clin Chem 2003;49:295302

We have to be really, really careful and thoughtful about using these medications in children and adolescents, said Cooper, noting that the long-term impacts of years of treatment in children are yet unknown

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