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After testing the fasting glucose concentrations, the mice were intraperitoneally injected with glucose (2 mg/g body weight, Sigma-Aldrich) for the GTT, or insulin (0.75 IU/g body weight, Novo Nordisk, Copenhagen, Denmark) for the ITT

COA on every batch

According to one large study in 9,075 people, having higher blood levels of vitamin B12 was associated with a lower risk of obesity ( Similarly, another study in 976 people showed that having low levels of vitamin B12 was linked to a higher risk of overweight or obesity ( Whats more, a study in 256 children showed that children with lower levels of vitamin B12 tended to have a higher body mass index (BMI), which is a measure of body size determined by height and weight ( However, keep in mind that while these studies show an association between vitamin B12 status and body weight, they dont take other potentially contributing factors into account

Taken together, these findings indicate that MALAT1 knockdown induces both apoptosis and ferroptosis while reducing cell viability in KGN cells