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We also highlight that nitrous oxide anesthesia should not be used in individuals who are at risk of vitamin B 12 deficiency
Followed by weekly, then monthly maintenance doses
Hydroxy B12 shots, though less effective, are safer, as this disease can get worse in those with high methylcobalamin levels
Research applications include NNMT pharmacology, methyltransferase signaling studies, enzymatic regulation investigations, and mechanistic evaluation of nicotinamide methylation pathways
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