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In its third-quarter results update this week, Novo Nordisk also revealed it has now filed for approval of oral semaglutide in the EU for launch in "selected markets," and sees the drug as "a big step forward in terms of expanding the market and for those individuals that align better with taking a pill for their obesity." Both companies have been investing heavily in direct-to-consumer (DTC) sales channels for cash purchasing of their current injectable products, and Novo Nordisk said on the call it will make oral semaglutide available across all its sales channels if approved.

Dihexa crosses the blood-brain barrier and activates the hepatocyte growth factor (HGF) / c-Met receptor pathway, which governs neuron survival and synapse formation

What we can say is that nothing in the existing data raises a specific concern about duration-dependent toxicity or organ damage that would accumulate over time

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy