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It has been postulated that the resulting excess of opioids affects brain maturation and causes autistic symptoms including : behavioral difficulties, attention problems, and alterations in communicative capacity and social and cognitive functioning

2.1.3 Metabolic reprogramming and dysfunction in immune cells Beyond the triggering of innate immune receptors, the perioperative environment profoundly affects immune cell metabolism, which in turn alters immune cell function

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De Backer G, Ambrosioni E, Borch-Johnsen K, Brotons C, Cifkova R, Dallongeville J, et al