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For research implications: if you want to study GH effects in isolation without the confounding effects of elevated cortisol (which is catabolic, immunosuppressive, and affects body composition) and prolactin Ipamorelin is the more appropriate tool
Tirzepatide may cause slightly stronger digestive symptoms early due to its dual-hormone action, while semaglutide may feel milder for some patients at first
Another study focusing on patients with type 2 diabetes found that tirzepatide not only improved blood sugar control but also resulted in weight loss ranging from 10% to 15% of body weight
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