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Chills are listed under the incidence not known category of side effects by the Mayo Clinic, indicating this effect has been observed, but its frequency is not well established
Glatigny S, Bettelli E
If you find yourself frequently needing to adjust your injection timing, discuss this pattern with your healthcare providerit may indicate that a different injection day would better suit your lifestyle
The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids
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