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To increase the translational potential of the available preclinical models, it has become necessary to devise humanised meal-schedule tasks in non-human primates and test the effects GLP1-R modulation on primate scheduled food intake, especially as only a limited number of studies are currently available to support the existing clinical findings and foster further research in the field
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This GLP-1RA features the C-terminal extension of exendin-4, which was sequentially added to the human GLP-1 sequence that includes two substitutions (aminoisobutyric acid (Aib) at position 2 and glutamic acid (Glu) at position 16) (Extended Data Fig
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