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35 It has improved steatosis, insulin resistance, and liver stiffness in short-term trials and is actively under clinical investigation as a treatment for MASH

Although severe TEAEs were infrequent overall, they increased with treatment intensity: 2% in the semaglutide group, 1.4% in the low-dose combination, 3.3% in the high-dose combination, and 10.1% in the triplet therapy arm

Like most side effects, ceasing semaglutide led to the symptoms dissipating

While most patients experience improved weight management, side effects like abdominal pain, injection site reactions, or mild gastrointestinal discomfort can occur