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A 2018 attempt by an independent lab to reproduce the headline neurotrophic effect in vitro reportedly produced mixed results, which is a typical finding when independent groups try to replicate striking preclinical findings
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Manna S, Mistri S, Zangrando E, Manna SC: The supramolecular assembly of tetraaqua-(pyridine-2, 5-dicarboxylato)-copper (II) complex: crystal structure, TD-DFT approach, electronic spectra, and photoluminescence study
The peptide in fact, can protect against prolongation of the QTc state of the heart in rats under daily administration of dopamine neuroleptics or prokinetics, which can lead to serious or even fatal arrhythmias
