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Side effects such as upper respiratory infection, low white blood cell count, and suicidality necessitate more extensive trials to confirm safety (Papp 2012
In laboratory settings, Dihexa is primarily investigated for its high-affinity interaction with hepatocyte growth factor (HGF) and its receptor, c-Met, serving as a primary tool to evaluate dendritic spine formation, synaptic plasticity, and neuroprotective cascades in established cell cultures and rodent models
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However, GLP-1 medications go a step further by not only improving insulin response but also by suppressing appetite and delaying gastric emptying , leading to more significant weight loss
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