is there oral glp 1 GLP-1 receptor agonists are generating a great deal of excitement as a potential inflection point in diabetes and obesity care. Amid the enthusiasm, however, a quieter and clinically important issue Oral GLP-1 Drugs: How the

doi: 10.3389/fmolb.2022.964624 Received 08 June 2022 Accepted 11 July 2022 Published 26 August 2022 Volume 9 - 2022 Edited by Giuseppe Calamita, University of Bari Aldo Moro, Italy Reviewed by Umberto Laforenza, University of Pavia, Italy Paul Yancey, Whitman College, United States Updates Copyright 2022 Ilyas, Wijayasinghe, Khan, El Samaloty, Adnan, Dar, Poddar, Singh, Sharma and Khan

Summary: GLP-1 receptor agonists can cause dizziness through mechanisms including hypoglycaemia, dehydration, orthostatic hypotension, and reduced caloric intake

Cortisol Awakening Response (CAR) Measures the cortisol increase just after waking, and helps to assess HPA axis dysfunction and stress resilience through the day

Notably, this effect was not apparent with shorter incubations (Fig