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However, further in vivo studies, including animal and human trials, are necessary to confirm the bioavailability of -EC in UDE and its potential therapeutic effects
Enhanced efficacy (via altered receptor trafficking and/or cross-talk) and/or potency (via entropic/avidity effects) may be obtained through possible multivalent receptor interactions in cells co-expressing the GLP-1R and the FGF21R (klotho/FGFR1c complex)
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