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Currently, for the injectable Wegovy, clinical evidence shows that it does not significantly reduce the bioavailability of combined oral contraceptives, which means the efficacy of the pills is not affected

Since its discovery in the periphery, the presence of PPG, GLP-1 and its receptor GLP-1R has also been reported in the central nervous system

However, detecting PCOS on a lab test requires a nuanced understanding of the condition, which isnt consistent across this range of disciplines, and irregular menstruation may not be a go-to area for investigation for areas like sleep, dermatology, hepatology and psychiatry, all of which PCOS can touch