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Changes in skin texture and elasticity A reduction in antioxidant protection can lead to subtle changes in skin smoothness, firmness, or brightness over time

Persistent or severe vomiting can lead to dehydration and other complications

The data we have comes largely from comparing separate trial populations, which introduces variables like differences in baseline BMI, diet and exercise protocols, and participant demographics

1 Beyond the weight-loss stress response, researchers have proposed several contributing mechanisms: Hormonal shifts , changes in insulin and insulin-like growth factor (IGF-1) signaling during rapid weight loss, may influence androgen activity and accelerate androgenetic alopecia in genetically predisposed patients