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Retatrutide adds GIP and glucagon signaling, but the Phase 3 side-effect list still looks recognizably incretin-based
Unlike a single-domain protein, recombinant multi-domain proteins are more likely to misfold or assemble in an incorrect 3D shape because of the interaction between their distinct domains
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Doctors are beginning to prescribe GLP-1s for younger children, but its off-label, meaning the drug hasnt been formally tested and approved for that age group
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