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Using prescription laxatives for long periods can cause dehydration, reliance on the medication, and other GI side effects like abdominal pain and bloating

While the evidence regarding GLP-1 receptor expression in testosterone-producing tissues is limited and mixed in humans, the metabolic changes induced by semaglutideparticularly significant weight loss and improved insulin sensitivitycan indirectly affect hormone balance

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We spoke with Seth Kipnis, M.D., a board-certified general surgeon and Medical Director of Bariatric and Robotic Surgery at Jersey Shore University Medical Center, and Ritu Anand, M.D., a board-certified endocrinologist at the Center for Weight Loss at JFK University Medical Center, to explain how bariatric surgery and GLP-1s work, who theyre best for, and what to expect so you can discuss the next right step with your care team