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Ms Murcia says: "We are in the early stages of developing new GLP-1 agonists derived from natural sources

Pasireotide may lead to hyperglycemia

Efficacy endpoints were change from baseline in HbA 1c and body weight (and, for the separate PIONEER 8 subgroup analysis, change from baseline in insulin dose) at the planned end of treatment (weeks 26, 52 or 78, according to the trial)