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Research reference Overview Cagrilintide is a long-acting synthetic analogue of the pancreatic hormone amylin, engineered with a fatty-acid side chain that extends its plasma half-life relative to native amylin
Human studies Human ILC2s were obtained from peripheral blood samples of five healthy anonymous adult volunteers, obtained following written consent
Both engineered receptors had a C-terminal MYC tag to allow detection of receptor surface expression by flow cytometry
10.1172/JCI138697 J Clin Invest
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