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Since GLP-1 receptor agonists enhance the effect of GLP-1, but only when the sugar is high, they have a lower risk of causing low blood sugar (hypoglycemia) than some medications
The maximum weight-loss results are typically seen after 6 to 12 months of consistent treatment
Factors that influence the decision include: baseline IGF-1 (lower IGF-1 may favor sermorelin to start), metabolic syndrome status (favors tesamorelin), visceral adiposity (favors tesamorelin), prior response to growth hormone-releasing peptides (helps calibrate dose), and patient tolerance preferences
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