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Prolonged usage of B6 and overdose can lead to CNS adverse effects, including ataxia
Magnetic resonance spectroscopy (MRS) allows to investigate the balance between the excitatory and inhibitory neuronal activities in the brains of living subjects, as this technology allows measuring excitatory glutamate (Glu), its relative metabolite glutamine (Gln), and the inhibitory gamma-aminobutyric acid (GABA) concentrations 13,14,15
Primary analysis using trial product estimand found that bodyweight was significantly decreased in the active treatment groups
G., Dostert, C
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