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Aegle marmelos , Mangifera indica , and Melicope glabra , which belong to the order Sapindales, have an IC 50 value against DPP-IV activity of 790, 182.7, and 169.40 g ml -1 (3335), respectively
These improvements occurred in both diabetic and non-diabetic patients, suggesting that GLP-1 activation itselfnot just weight losscontributes to lipid normalization
This difference may explain why overall cardiovascular outcomes remain favorable despite small increases in resting pulse
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