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This beneficial effect was supposedly due to the increased expression of genes involved in biotic stress response ( PR1 ), ethylene biosynthesis and ROS scavenging including a GST (Tiwari et al., 2016)
19 , 20 Briefly, the STEP-HFpEF trial was a randomized, international, multicenter, double-blind, placebo-controlled trial in patients with obesity phenotype of HFpEF and without type 2 diabetes
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