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used MYC-amplified breast cancer PDXs and employed Mini-PDX techniques to evaluate treatment responses in vivo

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Prog Neuropsychopharmacol Biol 19 : 117133 Forster EA, Cliffe IA, Bill DJ, Dover GM, Jones D, Reilly J, Fletcher A

10f-THF: 10-formyltetrahydrofolate 5mTHF: 5-methyltetrahydrofolate AICAR: P-ribosyl-5-amino-4-imidazole carboxamide CH = THF: 5-10-methenyltetrahydrofolate CH2-THF: 5-10-methylenetetrahydrofolate Cys: cysteine Cysta cystathionine DHF: dihydrofolate DMG: dimethylglycine dTMP: deoxythymidine monophosphate dUMP: deoxyuridine monophophate GAR: glycinamide ribonucleotide Glut: glutamate Glut: Cys glutamyl-cysteine Gly: glycine