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HO-1 has the potential to stimulate the angiogenesis by elevating the expression of several pro-angiogenic factors including VEGF, translational growth factor-1 (TGF-1), and stromal-derived factor-1 (SDF-1) [130, 131]
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Studies show that acetyl-L-carnitine may be helpful in improving peripheral neuropathy
The magnitude of enzyme improvement typically parallels the degree of weight loss achieved, though some hepatic benefits may occur independent of weight reduction
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